Pioneering Non-Surgical Solutions: Understanding the Impact of LH on Neonatal Pig Development

Inhibition of testicular development by suppressing neonatal LH rise in male domestic pigs

ChanJin Park, Sandra Soto-Heras, Lindsey Reinacher, Katie Chai, Sherry Zhou, Po-Ching Lin, Ji-Eun Oh, Mary Bunnell, Rex A. Hess, Luiz Renato de França, CheMyong Ko

We’re thrilled to congratulate our incredible team on the publication of their groundbreaking research examining the role of luteinizing hormone (LH) in testicular development of male pigs. This study sheds light on how neonatal treatment with a combination of estrogens and androgens can suppress LH secretion, ultimately inhibiting testicular growth. Through rigorous experimentation, the team discovered that while untreated piglets experienced a natural rise in LH levels, those receiving hormonal implants showed significantly lower concentrations, leading to notable changes in testicular size and function by 26 weeks of age.

This research not only enhances our understanding of reproductive physiology but also highlights our progress towards achieving our goal of developing non-surgical techniques for animal sterilization. Congratulations again to our team for their hard work and dedication to advancing knowledge in this vital area!